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Within the eastern and western clades, extensive linkage disequilibria existed between loci (measured by the index of association) (), suggesting that there were either genetically differentiated subpopulations or extensive clonal reproduction occurring within the existing populations.

Detection and quantification of Plasmodium falciparum in blood samples using quantitative nucleic acid sequence-based amplification.

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These findings indicate that gametocyte carriage is consistently underestimated by microscopy.

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Although these drugs are widely administered and are often used for prolonged periods, ocular side effects are rare and have been poorly described.

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It now appears these medications can be considered 'outdated' and fish treated quite successfully in either fish-only or possibly reef aquariums with an alternative product, with no harm to filtration bacteria!

What are the different plasmodium species causing malaria in India?

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Consistent with the immunoblotting results, confocal microscopic analyses showed that clioquinol markedly increased LC3-labeled puncta, an indicator of autophagosome formation, in a manner similar to starvation, but was abolished by 3-MA ().

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In contrast, combined treatment with CQ and TRAIL showed no morphological changes and did not increase sub-G1 population in TMCK-1 (mouse renal tubular epithelial cells) and MC (human mesangial cells) cells, differently from their effect in Caki cells ().

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Andriantsoanirina V, Ratsimbasoa A, Bouchier C, Tichit M, Jahevitra M, Rabearimanana S, Raherinjafy R, Mercereau-Puijalon O, Durand R, Menard D: Chloroquine clinical failures in Plasmodium falciparum malaria are associated with mutant pfmdr-1, not pfcrt in Madagascar.

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Furthermore, many water supply companies use chloramines rather than chlorine to treat the water that flows through their distribution networks, therefore recommend if needed using commercially prepared ammonia neutralizers that are often available through local aquarium shops.

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In fact, oxygen depletion - death by asphyxiation - can also result from 'excess' nitrogen being forced into solution, often caused by an improperly operating water pump and in such cases, entire collections of fish have been known to quickly die.

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Non-artemisinin combination therapy (ACT) drugs, especially SP and chloroquine (CQ), have partial activity against immature gametocytes.

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