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Within the eastern and western clades, extensive linkage disequilibria existed between loci (measured by the index of association) (), suggesting that there were either genetically differentiated subpopulations or extensive clonal reproduction occurring within the existing populations.

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Consistent with the immunoblotting results, confocal microscopic analyses showed that clioquinol markedly increased LC3-labeled puncta, an indicator of autophagosome formation, in a manner similar to starvation, but was abolished by 3-MA ().

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In contrast, combined treatment with CQ and TRAIL showed no morphological changes and did not increase sub-G1 population in TMCK-1 (mouse renal tubular epithelial cells) and MC (human mesangial cells) cells, differently from their effect in Caki cells ().

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Andriantsoanirina V, Ratsimbasoa A, Bouchier C, Tichit M, Jahevitra M, Rabearimanana S, Raherinjafy R, Mercereau-Puijalon O, Durand R, Menard D: Chloroquine clinical failures in Plasmodium falciparum malaria are associated with mutant pfmdr-1, not pfcrt in Madagascar.

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Comparison of the use of skin scarification and skin biopsies to determine the prevalence and intensity of Onchocerca volvulus infection.

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In fact, oxygen depletion - death by asphyxiation - can also result from 'excess' nitrogen being forced into solution, often caused by an improperly operating water pump and in such cases, entire collections of fish have been known to quickly die.

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Non-artemisinin combination therapy (ACT) drugs, especially SP and chloroquine (CQ), have partial activity against immature gametocytes.

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